Common reaction types substitution addition elimination and rearrangement - Question Bank
1. Which of the following is a characteristic of addition reactions to alkenes?
2. In the reaction of an alkyl halide with alcoholic KOH, the major product is usually the most substituted alkene according to:
3. The Fiest-Benary furan synthesis is an example of a reaction that involves:
4. Which reaction type involves the formation of a new sigma bond by breaking a pi bond?
5. What is the main product when tert-butyl bromide reacts with sodium hydroxide in aqueous solution?
6. The reaction of an alkene with ozone followed by a reducing agent (ozonolysis) is a type of:
7. A molecular rearrangement where a carbocation loses a proton is characteristic of which reaction type?
8. The reaction of an aldehyde or ketone with a Grignard reagent is an example of:
9. Which reaction involves the simultaneous removal of a leaving group and a proton from adjacent carbons?
10. The addition of a hydrogen halide to an unsymmetrical alkene follows Markovnikov's rule, meaning the hydrogen atom adds to:
11. Which of the following is a characteristic of E1 reactions?
12. The reaction of a primary alkyl halide with sodium ethoxide in ethanol can lead to both substitution and elimination. Which condition favors elimination?
13. Which of the following is an example of electrophilic substitution?
14. The pinacol rearrangement involves the acid-catalyzed rearrangement of:
15. Which reaction type is primarily responsible for the synthesis of alkenes from alcohols?
16. The reaction of ethene with water in the presence of sulfuric acid is an example of:
17. Which of the following is a characteristic of SN2 reactions?
18. The reaction of an alkene with KMnO4 under mild conditions (Baeyer's test) is an example of:
19. An E2 reaction requires:
20. Which of the following is an example of nucleophilic addition?
21. What is the driving force for many elimination reactions?
22. The addition of Br2 to cyclohexene results in:
23. Which rearrangement reaction involves the conversion of a ketone to an amide in the presence of sulfuric acid?
24. The reaction of a tertiary alkyl halide with a weak nucleophile in a protic solvent will likely proceed via:
25. Which type of reaction leads to the formation of a more unsaturated compound from a less unsaturated one?
26. What is the primary product when ethene reacts with HBr?
27. The rate of an SN2 reaction is dependent on the concentration of:
28. Which of the following reactions is an example of a rearrangement?
29. Dehydrohalogenation of alkyl halides is a type of:
30. Electrophilic addition to alkenes typically involves:
31. The reaction where a nucleophile replaces a leaving group on a saturated carbon atom is called:
32. Which of the following is a characteristic of SN1 reactions?
33. The reaction of an alkyl halide with a strong base like KOH in ethanol at reflux temperature primarily leads to:
34. The addition of a halogen to an alkyne typically occurs in how many steps?
35. Which of the following is NOT a common type of rearrangement reaction?
36. The Walden inversion is a characteristic feature of which substitution reaction?
37. In a free radical substitution reaction, which species initiates the chain mechanism?
38. The reaction of an alcohol with a strong acid (like H2SO4) at high temperature to form an alkene is an example of:
39. Which type of reaction is represented by the conversion of 2-bromopropane to propene?
40. The addition of H2O to an alkene in the presence of an acid catalyst follows which rule for regioselectivity?
41. Which reaction involves the migration of an alkyl or aryl group from one atom to another within the same molecule?
42. The conversion of an alkane to an alkene by removing two hydrogen atoms is an example of:
43. A carbocation intermediate is typically formed in which type of substitution reaction?
44. Which of the following conditions favors elimination reactions over substitution reactions?
45. The reaction of an alkene with a halogen (e.g., Br2) in the absence of a solvent is an example of:
46. Which mechanism is most commonly associated with SN2 reactions?
47. A rearrangement reaction is characterized by:
48. Which of the following is a classic example of a nucleophilic substitution reaction?
49. In an elimination reaction, what is typically removed from a molecule?
50. Which type of reaction involves the breaking of a pi bond and the formation of two new sigma bonds?